Since her earliest youth, Isabelle van Keulen has committed herself to chamber music, in all combinations and with all repertoire. As a child and young student she visited several chamber music courses and festivals, resulting in her early twenties to continuous invitations from Festivals like Lockenhaus Festival, Schleswig Holstein Musik Festival, Verbier Festival, Edindurgh Festival and many others.
She also founded her own festival, Delft Chamber Music Festival, in 1997, which she led till 2006.
With the Isos Quartet she made a recording of the Bruch string quartets, in 1997.
In 1990 she started a long musical relationship with Dutch pianist Ronald Brautigam, in the 23 years they have collaborated so far they made 10 recordings.
From 2006 till 2012 she was member of the Leopold String Trio; the most recent recordings were with Tanejev Trio's and Bach’s Goldberg Variations for the label Hyperion.
Since 2011 she has her own Tango Nuevo quartet, the Isabelle van Keulen Ensemble, with Christian Gerber, bandoneon, Ulrike Payer, piano and Rüdiger Ludwig, double bass. Apart from numerous appearances to come in summer 2013 at festivals like Schleswig Holstein, Rheingau, and concerts in Delft, Amsterdam, Den Haag, Haarlem they have just finished recording their first CD- and DVD-production for Challenge Classics, with several of Piazzolla’s master pieces.